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Faculty Profile

Dr. Paul Lepp


Paul Lepp, Ph.D.

Associate Professor of Biology

Office: 221 Cyril Moore Hall

Phone: (701) 858-3508

Email: paul.lepp@minotstateu.edu

Dr. Lepp received a B.A. in Biology from Gustavus Adolphus College, St. Peter, MN in 1990. In 1997 he earned his Ph.D. from Michigan State University in East Lansing, MI in the Department of Microbiology and Molecular Genetics and the Center for Microbial Ecology. From 1997 until 2004 Dr. Lepp was a Postdoctoral Fellow and a Research Associate at Stanford University School of Medicine in the Department of Microbiology and Immunology, where he worked on the microbial diversity associated with periodontitis funded by Procter & Gamble. Dr. Lepp joined the Biology faculty at Minot State in 2005.


Courses offered

Research Interests

        Dr. Lepp's research interests lie in the area of microbial ecology and evolution.  Molecular techniques are used address the identity and function of various microorganisms.  Current research projects include the characterization of a the microbial community within a cooling tower, the description and characterization of microorganisms capable of utilizating recalcitrant hydrocarbons and the modeling the rate of gene flow between engineered bacterial populations.

Recent Select Publications

Renko, J., K. Koskela, P. W. Lepp, N. Oksala, M. Levula, T. Lehtimäki, T. Solakivi, T. Kunnas, N. Oksala, S. Nikkari, S. T. Nikkari. 2013. Bacterial DNA signatures in carotid atherosclerosis represent both commensals and pathogens of skin origin. European Journal of Dermatology.

Ranko, J., P. W. Lepp, N. Oksala, S. Nikkari, S. T. Nikkari.  2008.  Bacterial signatures in atherosclerotic lesions represent human commensals and pathogens.  Atherosclerosis. 201(1):192-197.


Glatz, R. E., P. W. Lepp, B. B. Ward and C. A. Frances.  2006.  Planktonic microbial community composition across steep physical/chemical gradients in permanently ice-covered Lake Bonney, Antarctica.  Geobiol.  4:53-67.


Lepp, P. W., and T. M. Schmidt. 2004. Changes in Synechococcus population size and cellular ribosomal RNA content in response to predation and nutrient limitation. Microb. Ecol. 48(1):1-9.


Lepp, P. W., M. M. Brinig, C. C. Ouverney, K. Palm, G. C. Armitage, and D. A. Relman. 2004. Methanogenic Archaea associated with human periodontal disease. PNAS 101(16):6176-6181.

Cummings, C. A., M. M. Brinig, P. W. Lepp, S. van de Pas, and D. A. Relman. 2004. Bordetella species are distinguished by profiles of substantial and functionally relevant gene loss. J Bacteriol. 186(5):1484-92.

Maiwald, M., P. W. Lepp, and D. A. Relman. 2003. Analysis of conserved non-rRNA genes of Tropheryma whipplei. Syst. Appl. Microbiol. 26(1):3-12.

Brinig, M. M., P. W. Lepp, C. C. Ouverney, G. C. Armitage, and D. A. Relman. 2003. Prevalence of bacteria of division TM7 in human subgingival plaque and their association with disease. Appl. Environ. Microbiol. 69(3):1687-94.

Nikkari S., F. A. Lopez, P. W. Lepp, P. R. Cieslak, S. Ladd-Wilson, D. Passaro, R. Danila, and D. A. Relman. 2002. Broad-range bacterial detection and the analysis of unexplained death and critical illness. Emerg Infect Dis. 8(2):188-94.

Olivier, C., S. van de Pas, P. W. Lepp, K. Yoder, and D. A. Relman. 2001. Sequence variability in the first internal transcribed spacer region within and among Cyclospora species is consistent with polyparasitism. Int J Parasitol. 31(13):1475-87.


Fredricks, D. N, J. A. Jolley, P. W. Lepp, J. C. Kosek, and D. A. Relman. 2000. Rhinosporidium seeberi: a human pathogen from a novel group of aquatic protistan parasites. Emerg Infect Dis. 6(3):273-82.

Maiwald, M., A. von Herbay, P. W. Lepp, and D. A. Relman. 2000. Organization, structure, and variability of the rRNA operon of the Whipple's disease bacterium (Tropheryma whippelii).J Bacteriol. 182(11):3292-7.


Kroes, I., P. W. Lepp, and D. A. Relman. 1999. Bacterial diversity within the human subgingival crevice. Proc Natl Acad Sci U S A. 96(25):14547-52.


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